2019 · Podcast

GI Pearls – October 2019 – Episode 35 Gastroenterology Literature Review

Show Notes for Oct 2019 – Episode 35

  1. Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGH
  2. The View from Europe – TDM  – CGH 
  3. Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med.
  4. High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength – JAMA
  5. Safety of Endoscopy in Heritable Connective Tissue Disorders – Am J Gastro
  6. ASGE guideline on screening and surveillance of Barrett’s esophagus – ASGE
  7. Prucalporide in Gastroparesis: A Randomized Placebo-controlled Crossover Study. – Am J Gastro
  8. Over-Utilization of Repeat Upper Endoscopy in patients with non-dysplastic Barrett’s esophagus – Am J Gastro
  9. Controlling fecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomized clinical trial. – Lancet Gastro &Hep
  10.  Toshihiro Sugiyama  Understanding the Current Evidence on Proton Pump Inhibitor Use and Bone Health – Gastro
  11. Ursodeoxycholic acid versus placebo in women  with intrahepatic cholestasis of pregnancy (PITCHES):a randomised controlled trial – Lancet’
  12. Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial. –  JAMA Netw Open
  13. Association between soft drink consumption and mortality in 10 european countries. – JAMA
  14. Validation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients with Suspected Gastroparesis – CGH
  15. Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – NEJM
  16. Ustekinumab for Ulcerative Colitis – NEJM

2019 · Podcast

GI Pearls – September 2019 – Episode 34 Gastroenterology Literature Review

Show Notes for Sept 2019 – Episode 34

  1. Guidelines on management of cyclic vomiting  syndrome – Neurogastro and Motility
  2. Drug-induced Acute-on-Chronic Liver Failure in Asian Patients – Am J Gastro
  3. The efficacy of split-dose bowel prep for polyp detection: Meta-analysis – Am J Gastr
  4. Drug-induced liver injury – types and phenotypes – NEJM
  5. ASGE guideline on the role of endoscopy for bleeding from Chronic radiation proctopathy – GIE
  6. Efficacy of budesonide orodispensible tablets as induction therapy for EOE – randomized trial – Gastro
  7. Endoscopic control of polyp burden and expansion of surveillance intervals in serrated polyposis syndrome  – GIE
  8. Efficacy of FMT in IBS – Meta Analysis – Am J Gastr
  9. FMT in patients with PSC: Pilot clinical trial – Am J Gastr
  10. Nosocomial infections are frequent and negatively impact outcomes in hospitalized patients – Am J Gastro
  11. High immunogenicity of the PCV13 in immunocompromised adults with IBD – Am J Gastro
  12. Association of US News and World  Ranking for GI and GIOperation With Patient Outcomes in Abdominal Procedures- JAMA Surgery
  13. JAMA Clinical Guidelines Synopsis – CRC screening
2019 · Podcast

GI Pearls – June 2019 – Episode 33 Gastroenterology Literature Review

Show Notes for June 2019 – Episode 33

  1. Epidemiology and implications of concurrent diagnosis of EOE and IBD – Gut
  2. Risk of Cdiff Infection with Systemic  Antimicrobial Therapy Following Successful FMT –   Dig Dis Sci
  3. Safety of Endoscopy in cancer patients with thrombocytopenia and neutropenia – GIE
  4. Same-Day vs Different-Day Elective Upper and Lower Endoscopic Procedures by Setting – JAMA Internal Medicine
  5. Cuff-assisted versus cap-assisted colonoscopy for adenoma  detection: results of a randomized study – Endoscopy
  6. Promotion of Testing for Celiac Disese and the Gluten-Free diet among complementary and alternative medicine practitioners. – Am J Gastro
  7. Numbers and feature of Patient with a diagnosis of Celiac disease w/o Duodenal biopsy, based on a national survey – CGH
  8. Early colonoscopy for diverticular bleeding does not reduce risk of post-discharge recurrent bleeding :Propensity score matching analysis  – CGH
  9. AGA Clinical Practice Update on Interaction Between Oral DAAs for Chronic HepC Infection and HCC – Gastro
  10. Randomized placebo-controlled trial of droperidol and ondansetron for adult emergency department patients with nausea – Acad Emerg Med 
  11. Endoscopy-related musculoskeletal injuries in gastroenterology fellows – Endoscopy International
  12. Efficacy of MaziRenWan, a chinese Herbal medicine, in Patients with functional constipation – RTC – CGH
  13. Superiority of Gastrojejunostomy over Endoscopic Stenting for Palliation of Malignant gastric outlet obstruction – CGH

2019 · Podcast

GI Pearls – May 2019 – Episode 32 Gastroenterology Literature Review

Show Notes for May 2019 – Episode 32

  1. Risk of postpolypectomy bleeding with uninterrupted clopidogrel therapy- an industry-indepentend, double-blind, randomized trial. – Gastroenterology
  2. Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study – GUT
  3. Cold snare endoscopic resection of nonpedunculated colorectal polyps larger than 10mm: A systematic review and pooled analysis – GIE
  4. Weight Regain After Bariatric Surgery-A Multicentre Study of 9617 Patients from Indian Bariatric Surgery Outcome Reporting Group. – Obesity Surgery
  5. Resolution of NAFLD after bariatric surgery – CGH
  6. Risk of bacterial exposure to the endoscopist’s face during endoscopy – GIE
  7. Low Prevalence of Suspected Barrett’s Esophagus in patients with GERD without Alarm Symptoms – CGH
  8. Efficacy of  induction therapy with high intenstity Tofacitinib in 4 patients with acute severe UC – CGH
  9. Fecal Microbial Transplant Capsules are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo-Controlled Trial. – Hepatology
  10. Illuminating Elimination Diets: Controversies Regarding  Dietary Treatment of Eosinophilic Esophagitis – Dig Dis Sci
2019 · Podcast

GI Pearls – April 2019 – Episode 31 Gastroenterology Literature Review

Show Notes for April 2019 – Episode 31

  1. Prediction of individuals at high absolute risk of esophageal squamous cell carcinoma – GIE
  2. Updates on Gastric Intestinal Metaplasia – Digestive Diseases Sci
  3. Thermal ablation of mucosal defect margins reduces adenoma recurrence after colonic EMR – Gastro
  4. Transfusion Strategies for Acute Upper Gastrointestinal Bleeding – NEJM 
  5. Effect of restrictive versus liberal transfusion strategies on outcomes in patients with cardiovascular disease – BMJ 
  6. Outcomes following restrictive or liberal red blood cell transfusion in patients with lower gastrointestinal bleeding – AP&T
  7. Predicting the Course of Disease in Hospitalized  Patients With Acute Severe Ulcerative Colitis – IBD
  8. Fecal Microbiota Transplantation Is Superior to  Fidaxomicin for Treatment of Recurrent Clostridium difficile Infection – Gastro
  9. Hepatocellular Carcinoma – NEJM
  10. Non-invasive assessment of liver disease in patient with NAFLD. – Gastroenterology
  11. No association between pseudopolyps and colorectal neoplasia in patients with IBD – Gastro 
  12. Endoscopic sleeve gastroplasty versus laparoscopic sleeve gastrectomy: A case matched study. – GIE
  13. Glucocorticosteroids for people with alcoholic hepatitis. –  Cochrane Database Syst Rev.
  14. Switching between biologics and biosimilar in IBD – CGH
  15. Preventive medicine in IBD – CGH
Podcast

GI Pearls – March 2019 – Episode 30 Gastroenterology Literature Review

Show Notes for March 2019 – Episode 30

Sorry, but I was sick, so episode is shorter, and … late.

  1. Evaluation of adenomas per colonoscopy and adenomas per positive participant as new quality parameters in screening colonoscopy – GIE
  2. Adherence to Recommended Inpatient Hepatic Encephalopathy  Workup – J Hosp Med
  3. Clinical ipact and Safety of Anticoagulants for portal vein thrombosis – Am J Gastro
  4. Fracture risk in Patients with IBD: Nationwided population cohort study – Am J Gastro
  5. Comparing adenoma and polyp miss rates for total underwater colonoscopy versus standard CO2 – randomized trial using tandem colonoscopy approach.–  GIE
  6. Increasing adenoma detection rate in the right side of the colon comparing retroflexion with a second forward view: review – GIE
  7. Effects of bowel preparation on the human gut microbiome and metabolome– Scientific Reports
Podcast

GI Pearls – February 2019 – Episode 29 Gastroenterology Literature Review

Show Notes for February 2019 – Episode 29

  1. Effect of FMT on 8-week remission in patients with Ulcerative Colitis – RCT – JAMA 
  2. Inflammatory bowel disease increases the risk  of Parkinson’s disease – Gut
  3. Predictors of Metastases in Rectal  Neuroendocrine  Tumors: Results of a National Cohort  Study – Dis Colon Rectum.
  4. Long-term Risk of Colorectal Cancer and Related  Deaths After a Colonoscopy With Normal Findings – JAMA Internal Med
  5. Single-stage EUS-guided choledochoduodenostomy using a lumen-apposing metal stent for malignant distal biliary obstruction – GIE 
  6. Refractory ascites in Liver Cirrhosis – Am J Gastro
  7. Choosing the right through-the-scope clip: a rigorous comparison… – GIE
  8. Emergent Colon Resections: Does  Surgeon Specialization Influence Outcomes? – Diseases of Colon&Rectum
  9. Dietary Gluten Intake and Risk of Microscopic Colitis in US women without Celiac Disease – Prospective Cohort Study – Am J Gastr
  10. To scope or not to scope? The safety of Upper Endoscopy in the Setting of Pulmonary Embolism. – Am J Gastr
Podcast

GI Pearls – January 2019 – Episode 28 Gastroenterology Literature Review

Show Notes for January 2019 – Episode 28

  1. Diagnosis and treatment of definitive diverticular hemorrhage – AmJGastro
  2. Proton-pump inhibitor prophylaxis in the ICU – NEJM
  3. Effectiveness and Safety of Reference  Infliximab and Biosimilar in Crohn Disease: A French Equivalence Study – Annals of IM
  4. Laparoscopic magnetic sphincter augmentation versus double-dose PPI for GERD, randomized controlled trial – GIE
  5. Evolving considerations for thiopurine therapy for IBD – Clinical Practice Update: Commentary – Gastro
  6. Incidence, risk factors and clinical effects of recurrent diverticular hemorrhage: a large cohort study – Gastro
  7. Etiological spectrum and response to endoscopic balloon dilation in patients with benign gastric outlet obstruction – GIE
  8. Pancreatic Cancer Following acute pancreatitis: a population-based matched cohort study – AmJGastro
  9. Trainee colonoscopy quality is influenced by the independent and unobserved performance characteristics of supervising physicians – Endoscopy International Open
  10. Tofacitinib Induction Therapy Reduces Symptoms  Within 3 Days for Patients With Ulcerative Colitis – CGH
  11. Telehealth-Based Evaluation identifies Patients who are not candidates for liver transplantation – CGH
  12. An RCT comparing efficacy of early video capsule endoscopy with standard of care in the approach to nonhematemesis GI bleeding – GIE

Feel free to leave comments about the episode or the articles online at GIpearls.com – just go to the individual episode page.

Podcast

GI Pearls – December 2018 – Episode 27 Gastroenterology Literature Review

Show Notes for December 2018 – Episode 27

  1. Efficacy of ustekinumab for inducing endoscopic healing in patients with Crohn’s disease – Gastro
  2. Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding – JAMA
  3. Clinician Guide to Microbiome Testing – Dig Dis Sci
  4. Stopping 5-ASA in patients with UC starting biolocig therapy does not increase risk of adverse clinical outcomes – Gut Journal
  5. Effect of Aspirin on disability-free survival in the healthy elderly. – NEJM
  6. Hyperbaric oxygen therapy for UC patients hospitalized for moderate-severe flares – Am J Gastro
  7. Mortality due to cirrhosis and liver cancer in the United  States, 1999-2016: observational study – BMJ 
  8. No association between screening for HCC and reduced cancer-related mortality in patietns with Cirrhosis –  Gastro
  9. Exposure concentrations of infants breastfed by women receiving biologic therapies for IBD  – Gastro
  10. Comparative effectiveness and safety of Bariatric Procedures for Weight loss – Annals of IM
  11. Risk of esophageal adenocarcinoma after anti-reflux surgery in patients with GERD – Jama Oncology
  12. Guideline – Screening for CRC in individuals with family history of nonhereditary colorectal cancer or adenoma – Gastro
Podcast

GI Pearls – November 2018 – Episode 26 Gastroenterology Literature Review

Show Notes for November 2018 – Episode 26
I’ve changed the intro music, obviously, let me know if you are annoyed by it or like it. Here is the list of papers:
  1. The Essential Medicinal Chemistry of Curcumin – Journal of Medicinal Chemistry
  2. Everything is awesome: Don’t forget the Lego – J of Peds and Child Health.