2021 · Podcast

Episode 52 – November 2021 – Gastroenterology Literature Review

Episode 52 Show notes

  1. Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis – NEJM
  2. Benchmarking Adenoma Detection Rates for Colonoscopy: Results From a US-Based Registry – Am J Gastro
  3. Colonoscopy-related Mortality in a Fecal-Immunochemical Test-based Colorectal Cancer Screening Program – CGH
  4. AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in IBD – expert review – Gastro
  5. Should Treatment Indications for Chronic Hepatitis B be  Expanded? – CGH
  6. Urinary Cannabis Metabolite Concentrations in Cannabis Hyperemesis Syndrome  – JPGN
  7. A randomized, Controled Trial of the Pan-PPAR Agonist Nanifibranor in NASH – NEJM
  8. Prospective study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease – NEJM
  9. Recommendation Reversals in Gastroenterology Clinical Practice Guidelines – J of Canadian A of Gastro
2021 · Podcast

Episode 51 – September 2021 – Gastroenterology Literature Review


Show notes for Episode 51

  1. Role of routine second-look endoscopy in patients with acute peptic ulcer bleeding: meta-analysis of randomized controlled trials-  GIE
  2. A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn’s Disease – Gastroenterology
  3. Comparative effectiveness and harms of antibiotics for outpatient diverticulitis. – Annals of IM
  4. Colonoscopy Versus Fecal Immunochemical Test for Reducing Colorectal Cancer Risk: A Population-Based Case–Control Study   – CTG
  5. Combination therapy does not improve rate of clinical or endoscpic remission in patients with IBD treated with vedolizumab or ustekinumab. – CGH
  6. World Gastroenterology Organisation Global Guidelines –  Helicobacter Pylori May 2021
  7. Gene-Specific Variation in Colorectal Cancer Surveillance Strategies for Lynch Syndrome
  8. Association between time to colonoscopy after positive fecal testing and colorectal cancer outcomes: Review – CGH
  9. Intestinal Failure: What all gastroenterolgists should know-  CGH
  10. ACG Clinical Guidelines: Prevention, Diagnosis and TReatment of Clostridioides difficile Infections – Am J Gastro
2021 · Podcast

Episode 50 – May 2021 – Gastroenterology Literature Review

  1. Histologic Changes caused by Injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. – GIE
  2. Prevalence of Barrett’s Esophagus and performance of societal screening guidelines in an unreferred Primary care Population of US veterans.  – GIE
  3. The usefulness of olive oil enema in children with severe chronic constipation – J Ped Surg
  4. Rates of Postoperative Recurrence of Crohn’s Disease and Effects of Immunosuppresive and Biologic Therapies – CGH
  5. Histopathologic features and fragmentation of polyps with cold snare defect protrusions. – GIE
  6. AGA Clinical Practice Update on Diagnosis and Management of Immune Checkpoint Inhibitor Colitis – Gastro
  7. Management and outcomes of bleeding within 30 days of colonic polypectomy in a Large, Real-Life, Multicenter Cohort study. – CGH
  8. Hypothermic Machine Perfusion in Liver Transplantation – NEJM
  9. EUS-guided gallbladder drainage vs laparoscopic cholecystectomy for acute cholecystitis: a propensity score analysis with 1-year follow up data.  – GIE
  10. The prevalence of small-bowel polyps on video capsule endoscopy in patients with sporadic duodenal or ampullary adenomas. – GIE
  11. Adverse events and residual lesions rate after cold endoscopic mucosal resection of serrated lesions >10mm.
  12. Colorectal EMR outcomes in octogenarians versus younger patients referred for removal of large (>20mm) non-pedunculated polyps. – GIE
2021 · Podcast

Episode 49 – April 2021 – Gastroenterology Literature Review

Show notes for Episode 49 for April 2021

  1. Effectiveness of Oral Vancomycin for Prevention of Healtchare Facility-onset C.diff infection in Targeted Patients during Systemic antibiotic Exposure – Clinical ID
  2. The Detrimental Effects of oral Vancomycin – Letter to Editor – Clinical ID
  3. Linked color imaging focused on Neoplasm detection in the Upper GI tract – randomised trial  – Annals of Internal Medicine
  4. AGA clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review
  5. Comparative effectiveness and harms of antibiotics for outpatient diverticulitis: Two nationwide cohort studies. Ann Intern Med
  6. Effects of Tenofovir vs Entecavir on Risk of HCC in patients with chronic HBV infection: A SRMA – CGH
  7. Factors that affect adequacy of Colon cleansing for colonoscopy in Hospitalized Patients – CGH
  8. https://app.calculoid.com/#/calculator/69490
  9. ACG Clinical Guidelines: Colorectal Cancer Screening 2021
2021 · Podcast

Episode 48 – March 2021 – Gastroenterology Literature Review

Show notes for Episode  48 March 2021

  1. Younger physicians and longer withdwaral times are associated with detection of advanced neoplasia in a large community practice. – CGH
  2. It’s All The RAVE: Time to Give up on “Chronic Radiation Proctitis” Misnomer – Gastroenterology
  3. Local immune response to food antigens drives meal-induced abdominal pain – Nature
  4. Prevalence of  a First-Degree Relative with Colorectal Cancer and Uptake of screening among persons 40-54 years old. – CGH
  5. Prevalence of IBS-type symptoms in patients with IBD in remission: SRMA – Lancet:Gastro and Hep
  6. Impact of 9-Minute Withdrawal Time on the Adenoma  Detection Rate: A Multicenter Randomized Controlled Trial –  CGH
  7. Use of proton pump inhibitors to treat persistent throat symptoms: multicentre, double blind, randomised, placebo controlled trial – BMJ
  8. Effects of Colesevelam on Bowel Symptoms, Biomarkers, and Colonic Mucosal gene Expression in Patients with Bile Acid Diarrhea in a Randomized Trial. – CGH
  9. Possible tumour cell reimplantation during curative endoscopic therapy of superficial Barrett’s carcinoma – GUT
  10. Pneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomized sham-controlled clinical trial. – GUT 
  11. Efficacy of Therapy for EOE in Real-World Practice – CGH
  12. ACG Clinical Guideline: Management of Irritable Bowel Syndrome – ACG

FYI – if you need me to send you the article, please e-mail me, and I will.

2021 · Podcast

Episode 47 – January 2021 – Gastroenterology Literature Review

Show notes for Episode  47, January 2021

  1. Endoscopic Recognition and management strategies for Malignant Colorectal Polyps: Recommendation of the US Multi-Society Task force on Colorectal Cancer – GIE
  2. Polyp morphology: an interobserver evaluation for the Paris classification among international experts – AmJ Gastro
  3. Outcomes in lower GI bleeding comparing weekend with weekday admission. – GIE
  4. Efficacy and Safety of Ornithine Phenylacetate for Treating Overt Hepatic Encephalopathy in a Randomized Trial  – CGH
  5. A Trial of Ornithine Phenylacetate and the Arc of Ammonia’s History for Overt Hepatic Encephalopathy – CGH
  6. Are Gastrointestinal Symptoms Specific for Coronavirus 2019 Infection? A Prospective Case-Control Study from the United States – Gastro
  7. A randomized trial comparing antibiotics with appendectomy for appendicitis. – NEJM
  8. FIT test after negative colonoscopy may reduce the risk of incident colorectal cancer in a population-based screening programme – GUT
  9. The efficacy and safety of Vitamin C for Iron Supplementation in Adult Patients with Iron Deficiency Anemia – Jama Open
  10. Randomised comparison of postpolypectomy surveillance intervals following a two-round baseline colonoscopy.  – GUT 
  11. Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis – CGH
  12. Comparing Laparoscopic Elective Sigmoid Resection with Conservative Treatment in improving QoL of Patients with Diverticulitis. – JAMA Surgery

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2020 · Podcast

GI Pearls – December 2020 – Episode 46 Gastroenterology Literature Review

Show notes for Episode 46 for December 2020

  1. Sequential endoscopist-driven phone calls improve capture rate of adverse events after ERCP: a prospective study – GIE 
  2. Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies – GUT 
  3. Long-Term Consequences of Undiagnosed Celiac seropositivity –  Am J Gastro
  4. Hyperbaric oxygen therapy is effective in the treatment of inflammatory and fistulizing pouch complications. – CGH
  5. Evaluating the optimum number of biopsies to  assess histological inflammation in ulcerative colitis: a  retrospective cohort study – Alimentary Pharmacology&Ther
  6. Neutrophil-to-lymphocyte ratio and risk of neoplastic progression  in patients with Barrett’s esophagus  – Endoscopy
  7. Empirical Treatment With Carbapenem vs  Third-generation Cephalosporin for Treatment of  Spontaneous  Bacterial Peritonitis
  8. Combination Therapy of Adalimumab With an Immunomodulator Is Not More Effective Than Adalimumab Monotherapy in Children With Crohn’s Disease: A Post Hoc Analysis of the PAILOT Randomized Controlled Trial – IBD journal
  9. Treatment of Gut Fermentation Syndrome with FMT – Annals of IM
  10. A Prospective evaluation of POCUS diagnosis of diverticulitis in the emergency Department – Ann Emerg Med 2020 
  11. The long-term outcomes and natural disease course of serrated polyposis syndrome: over 10 years of prospective follow-up in a specialized center – GIE

2020 · Podcast

GI Pearls – November 2020 – Episode 45 Gastroenterology Literature Review

Show notes for Episode 45 for November 2020

  1.  Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude – CGH
  2. Early Colonoscopy Does Not Improve Outcomes of  Patients With Lower Gastrointestinal Bleeding: SRM – CGH 
  3. Adverse Events After Inpatient Colonoscopy in Octogenarians – J of Clinical Gastro
  4. Comparative Efficacy of Drugs for the Treatment of Chronic Constipation – J of Clinical Gastro
  5. Two vs one forward view examination of right colon on adenoma detection: an international multicenter randomized trial – CGH
  6. Effects of Time-Restricted Eating on Weight Loss and Other  Metabolic Parameters in Women and Men With Overweight and Obesity – Jama Internal Medicine
  7. Anti–Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis – NEJM
  8. Coexistent faecal incontinence and constipation: A cross-sectional study of 4027 adults undergoing specialist assessment – EClinical Medicine
  9. Meta-analysis of Virtual-based Chromoendoscopy  Compared With Dye-spraying Chromoendoscopy Standard  and  High-definition White Light Endoscopy in Patients  With Inflammatory Bowel Disease at Increased Risk of  Colon Cancer – IBD journal

2020 · Podcast

GI Pearls – October 2020 – Episode 44 Gastroenterology Literature Review

Show Notes for October 2020 – Episode 44

  1. A Quarter of Participants With Advanced Neoplasia  Have Discordant Results From 2-Sample Fecal  Immunochemical Tests for Colorectal Cancer Screening – CGH
  2. Assessment of Clinical Conditions Associated with Splenic Infarction in Adult Patients – JAMA Internal Medicine
  3. Unsedated colonoscopy – impact on quality indicators – Dig Dis Sci
  4. The effect of green kiwifruit on gas transit and tolerance in healthy humans – Neurogastroenterology & Motility
  5. Second international Guidelines for the Diagnosis and Management of HHT – Annals of IM
  6. AGA Clinical Practice Guidelines on the  Gastrointestinal  Evaluation of Iron Deficiency Anemia – GASTRO
  7. AGA Clinical Practice Guidelines on the Role of  Probiotics in the Management of Gastrointestinal Disorders – Gastro 
  8.  Interview with Jonathan Tsoni Peled, MD/PhD from Memorial Sloan Kettering in NYC.  Twitter: @tsonipeled 

2020 · Podcast

GI Pearls – September 2020 – Episode 43 Gastroenterology Literature Review

Show notes for Episodes 43 – September 2020

  1. Levels of Vitamin D are low after Crohn’s disease is established but not before –  CGH
  2. Rapid recurrence of EOE activity after successful treatment in the observational phase of a randomised trial. – CGH
  3. Clinical outcomes of adults with eosinophilic esophagitis with severe stricture. – GIE
  4. Quality of Colonoscopy: A Comparison  Between  Gastroenterologists and  Nongastroenterologists – Dis of colon & Rectum.
  5. A Novel Score to Predict Esophageal Varices in Patients  with Compensated Advanced Chronic Liver Disease – DDS
  6. https://cookcountyscore.shinyapps.io/cookcountyscore/ 
  7. Outcomes of Gallbladder Polyps and Their Association With Gallbladder Cancer in a 20-Year Cohort   – JAMA Network
  8. Discordance Between Patient-Reported Outcomes  and Mucosal Inflammation in Patients With Mild to  Moderate Ulcerative Colitis – CGH
  9. Rifabutin-Based triple therapy for Hpylori Eradication – Annals of IM
  10. Does Gastric Bypass Improve Glycemic Control Beyond the Effect of Weight Loss? – NEJM
  11. Regression of Fibrosis Stage With Treatment  Reduces Long-Term Risk of Liver Cancer in Patients w/ Hemochromatosis Caused by Mutation in HFE  – CGH