2020 · Podcast

GI Pearls – June 2020 – Episode 41 Gastroenterology Literature Review

Show notes for Episodes 41 – June 2020

  1. Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polyps – GIE
  2. AGA Guidelines on the management of Moderate to Severe Ulcerative Colitis – Gastro 
  3. Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. – CGH
  4. Reduced incidence of Hepatic encephalopathy and higher odds of resolutions associated with eradication of HCV – CGH
  5. Ammonia Levels do not guide clinical management of patients with hepatic encephalopathy caused by cirrhosis. – Am J Gastro
  6. Low-Value Levels: Ammonia Testing Does not Improve the Outcomes of HE. – Am J Gastro
  7. Young adults and metachronous neoplasia: risks for future advanced adenomas and large serrated polyps compared with older adults – GIE
  8. Changing patters in the epidemiology and outcomes of IBD in the UK – 2000-2018 – AP&T 
  9. Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: SRMA – Am J Gastro
  10. Low incidence of aerodigestive cancers in patients with negative results from colonoscopies, regardless of findings from stool DNA tests. – CGH 
  11. Endoscopic retrieval of magnetic foreign body ingestions with  a nasal bridle: description of a novel technique – GIE
  12. Underwater versus conventinal endoscopic resection of nondiminutive nonpedunculated colorectal lesions: RCT – GIE
  13. Cancer Prevention With Aspirin in Hereditary Colorectal Cancer (Lynch Syndrome), 10-year Follow-Up – Lancet
  14. AGA and Allergy Immunology Guidelines for EOE – Gastro

2020 · Podcast

GI Pearls – May 2020 – Episode 40 Gastroenterology Literature Review

Show notes for Episodes 40 – May 2020

  1. Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro
  2. Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med
  3. Diagnosis and Treatment of Clostridioides (Clostridium) difficile  Infection  in Adults in 2020 – JAMA
  4. Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: multicenter randomized controlled trial (PRESECT study). –  GIE
  5. Timing of endoscopy for Acute Upper Gastrointestinal Bleeding – NEJM
  6. Trends in US Burden of C.difficile infection – NEJM
  7. Mechanism, Evaluation and Management of Chronic Constipation – Gastroenterology
  8. Undisclosed payments by pharmaceutical and medical device manufacturers to authors of endoscopy guidelines in the United States – GIE
  9. Managing conflicts of interest in clinical practice guidelines – GIE
  10. Hepatopulmonary Syndrome – NEJM
  11. Reversal of Digital Clubbing After Lung Transplantation in Cystic Fibrosis Patients:  A Clue to the Pathogenesis of Clubbing – Pediatr Pulmonol.
  12.  Infectious Proctitis – NEJM 
  13.  Intestinal Lipomatosis – NEJM
  14.  EUS-guided gastroenteric anastomosis as a bridge to  definitive treatment in benign gastric outlet obstruction – GIE
  15. Uptake of Colorectal Cancer Screening by Physicians  Is  Associated With Greater Uptake by Their Patients – Gastro
  16. Immunosuppression in Autoimmune Hepatitis: Is There an End Game? – Am J Gastro
2020 · Podcast

GI Pearls – March/April 2020 – Episode 39 Gastroenterology Literature Review

Show notes for Episodes 39 – February-March 2020

  1. Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIE
  2. Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournal
  3. Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastro
  4. Risk of progression of Barrett’s esophagus indefinite for dysplasia: Meta-analysis – GIE
  5. AGA Clinical Pratice Update – Management of Pancreatic Necrosis – Gastro
  6. Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents – Cell
  7. Neutropenic Enterocolitis: Clinical  Features and Outcomes – Dis Colon Rectum. 
  8. Long-term Risk of Malignancy in Branch-Duct  Intraductal Papillary Mucinous Neoplasms – Gastro
  9. Increased incidence and Mortality of Gastric Cancer in Immigrant Population from High to Low Regions of Incidence: Systematic Review – CGH
  10. AGA: Clinical Practice Guidelines on management of Gastric Intestinal Metaplasia – Gastro

2020 · Podcast

GI Pearls – January 2020 – Episode 38 Gastroenterology Literature Review

Show notes for Episodes 38 – January 2020

  1. ASGE review of adverse events in colonoscopy – GIE 
  2. Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia – NEJM
  3. Relationship Between Recreational Marijuana  Use and Bowel Function in a Nationwide Cohort Study – Am J gastro
  4. Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and  screening for colorectal cancer – Science TM
  5. Lactulose Breath Testing as a Predictor of  Response to Rifaximin in Patients With Irritable bowel  Syndrome With Diarrhea – AmJ Gastro
  6. Postinfectious IBS after Campylobacter infection – Am J Gastro
  7. Oral Curcumin no more effective than placebo in preventing recurrence of Crohn’s disease after surgery in RTC – CGH
  8.  Hpylori – when treat when not to treat – Am J Gastro
  9. Long-Duration Oral Vancomycin to treat Cdiff in patients iwth IBD is associated with low rate of recurrence – Am J Gastro
  10. Masked bolus gluten challenge low in FODMAPs implicates nausea and vomiting as key shymptoms of exposure to celiac – AP&T
  11. Clinical and molecular features of post-colonoscopy colorectal cancers – CGH
  12. Simethicone use during gastrointestinal endoscopy: Position statement of the Gastroenterological Society of Australia – Journal of Gastro&Hep
Podcast

GI Pearls – December 2019 – Episode 37 Gastroenterology Literature Review

Show Notes for December 2019 – Episode 37

  1. Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med.
  2. Association between Hpylori exposure and decreased odds of EOE – CGH
  3. Effect of anti-Hpylori therapy on incidence of autoimmune diseases,  – CGH
  4. AGA Practice Update on Surveillance for cancer in patients with PSC – Gastro.
  5. Screening for colorectal cancer in asymptomatic average-risk adults: ACP guideline – Annals of Int Med
  6. High intensity versus low intensity surveillance for patients with colorectal adenomas – Annals of Int med
  7. Infliximab-Tumor Necrosis Factor complexes Elicif formation of Anti-Drug Antibodies – Gastro
  8. Outcomes of Patients with IBD switched from maintenance therapy with a biosimilar to Remicade – CGH
  9. Lactose drives Enterococcus expansion to promote graft-versus-host disease – Science 
  10. The association between dietary fiber deficiency and high-income lifestyle-associated diseses: Burkitt’s hypothesis revisited. 
  11. Compared abilities of endoscopic techniques to increase colon adenoma detection rates – CGH
  12. Advanced imaging for detection and differentiation of colorectal neoplasia:ESGE Guidelines – Endoscopy
Podcast

GI Pearls – November 2019 – Episode 36 Gastroenterology Literature Review

Show Notes for November 2019 – Episode 36

  1. Detection of Various Microplastics in Human stool – Annals of int Med
  2. Herpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care Res
  3. Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae  – Cell
  4. Incidence of and Risk Factors for  Hepatic Encephalopathy in a Population-Based Cohort of Americans – Hepatology Communications
  5. FFP transfusion in patients with cirrhosis and coagulopathy: effect on conventional coagulation tests and thrombomodulin-modified thrombin generation  – J Hepatol.
  6. Effect of Chromoendoscopy in the proximal colon on Colorectal neoplasia detection in Lynch syndrome: A multicenter randomized controlled trial. – GIE
  7. Terminology, Molecular featuers, Epidemiology, and Management of Serrated Colon neoplaisa.
  8. Providing data for serrated polyp detection rate benchmarks – GIE 
  9. Management of Nonvariceal Upper GI bleeding: Guideline recommendations from the International Consensus Group – Ann of Int Med
  10. Efficacy of Prophylactic Hemoclips in prevention of delayed post-polypectomy Bleeding in patients with large colonic polyps – Gastro
  11. Clip Closure Prevents Bleeding After Endoscopic resection of large colon polyps in a randomized trial – Gastro

2019 · Podcast

GI Pearls – October 2019 – Episode 35 Gastroenterology Literature Review

Show Notes for Oct 2019 – Episode 35

  1. Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGH
  2. The View from Europe – TDM  – CGH 
  3. Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med.
  4. High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength – JAMA
  5. Safety of Endoscopy in Heritable Connective Tissue Disorders – Am J Gastro
  6. ASGE guideline on screening and surveillance of Barrett’s esophagus – ASGE
  7. Prucalporide in Gastroparesis: A Randomized Placebo-controlled Crossover Study. – Am J Gastro
  8. Over-Utilization of Repeat Upper Endoscopy in patients with non-dysplastic Barrett’s esophagus – Am J Gastro
  9. Controlling fecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomized clinical trial. – Lancet Gastro &Hep
  10.  Toshihiro Sugiyama  Understanding the Current Evidence on Proton Pump Inhibitor Use and Bone Health – Gastro
  11. Ursodeoxycholic acid versus placebo in women  with intrahepatic cholestasis of pregnancy (PITCHES):a randomised controlled trial – Lancet’
  12. Effect of Bismuth Subsalicylate vs Placebo on Use of Antibiotics Among Adult Outpatients With Diarrhea in Pakistan: A Randomized Clinical Trial. –  JAMA Netw Open
  13. Association between soft drink consumption and mortality in 10 european countries. – JAMA
  14. Validation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients with Suspected Gastroparesis – CGH
  15. Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis – NEJM
  16. Ustekinumab for Ulcerative Colitis – NEJM

2019 · Podcast

GI Pearls – September 2019 – Episode 34 Gastroenterology Literature Review

Show Notes for Sept 2019 – Episode 34

  1. Guidelines on management of cyclic vomiting  syndrome – Neurogastro and Motility
  2. Drug-induced Acute-on-Chronic Liver Failure in Asian Patients – Am J Gastro
  3. The efficacy of split-dose bowel prep for polyp detection: Meta-analysis – Am J Gastr
  4. Drug-induced liver injury – types and phenotypes – NEJM
  5. ASGE guideline on the role of endoscopy for bleeding from Chronic radiation proctopathy – GIE
  6. Efficacy of budesonide orodispensible tablets as induction therapy for EOE – randomized trial – Gastro
  7. Endoscopic control of polyp burden and expansion of surveillance intervals in serrated polyposis syndrome  – GIE
  8. Efficacy of FMT in IBS – Meta Analysis – Am J Gastr
  9. FMT in patients with PSC: Pilot clinical trial – Am J Gastr
  10. Nosocomial infections are frequent and negatively impact outcomes in hospitalized patients – Am J Gastro
  11. High immunogenicity of the PCV13 in immunocompromised adults with IBD – Am J Gastro
  12. Association of US News and World  Ranking for GI and GIOperation With Patient Outcomes in Abdominal Procedures- JAMA Surgery
  13. JAMA Clinical Guidelines Synopsis – CRC screening
2019 · Podcast

GI Pearls – June 2019 – Episode 33 Gastroenterology Literature Review

Show Notes for June 2019 – Episode 33

  1. Epidemiology and implications of concurrent diagnosis of EOE and IBD – Gut
  2. Risk of Cdiff Infection with Systemic  Antimicrobial Therapy Following Successful FMT –   Dig Dis Sci
  3. Safety of Endoscopy in cancer patients with thrombocytopenia and neutropenia – GIE
  4. Same-Day vs Different-Day Elective Upper and Lower Endoscopic Procedures by Setting – JAMA Internal Medicine
  5. Cuff-assisted versus cap-assisted colonoscopy for adenoma  detection: results of a randomized study – Endoscopy
  6. Promotion of Testing for Celiac Disese and the Gluten-Free diet among complementary and alternative medicine practitioners. – Am J Gastro
  7. Numbers and feature of Patient with a diagnosis of Celiac disease w/o Duodenal biopsy, based on a national survey – CGH
  8. Early colonoscopy for diverticular bleeding does not reduce risk of post-discharge recurrent bleeding :Propensity score matching analysis  – CGH
  9. AGA Clinical Practice Update on Interaction Between Oral DAAs for Chronic HepC Infection and HCC – Gastro
  10. Randomized placebo-controlled trial of droperidol and ondansetron for adult emergency department patients with nausea – Acad Emerg Med 
  11. Endoscopy-related musculoskeletal injuries in gastroenterology fellows – Endoscopy International
  12. Efficacy of MaziRenWan, a chinese Herbal medicine, in Patients with functional constipation – RTC – CGH
  13. Superiority of Gastrojejunostomy over Endoscopic Stenting for Palliation of Malignant gastric outlet obstruction – CGH

2019 · Podcast

GI Pearls – May 2019 – Episode 32 Gastroenterology Literature Review

Show Notes for May 2019 – Episode 32

  1. Risk of postpolypectomy bleeding with uninterrupted clopidogrel therapy- an industry-indepentend, double-blind, randomized trial. – Gastroenterology
  2. Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study – GUT
  3. Cold snare endoscopic resection of nonpedunculated colorectal polyps larger than 10mm: A systematic review and pooled analysis – GIE
  4. Weight Regain After Bariatric Surgery-A Multicentre Study of 9617 Patients from Indian Bariatric Surgery Outcome Reporting Group. – Obesity Surgery
  5. Resolution of NAFLD after bariatric surgery – CGH
  6. Risk of bacterial exposure to the endoscopist’s face during endoscopy – GIE
  7. Low Prevalence of Suspected Barrett’s Esophagus in patients with GERD without Alarm Symptoms – CGH
  8. Efficacy of  induction therapy with high intenstity Tofacitinib in 4 patients with acute severe UC – CGH
  9. Fecal Microbial Transplant Capsules are Safe in Hepatic Encephalopathy: A Phase 1, Randomized, Placebo-Controlled Trial. – Hepatology
  10. Illuminating Elimination Diets: Controversies Regarding  Dietary Treatment of Eosinophilic Esophagitis – Dig Dis Sci